A Mild and Efficient Method for the Stereoselective Formation of C-O Bonds: Palladium-Catalyzed Allylic Etherification
Using Zinc(II) Alkoxides

Hahn Kim, Chulbom Lee

Org. Lett. 4, 4369-4371 (2002). DOI

Probing the SAR of dEpoB via Chemical Synthesis:
A Total Synthesis Evaluation of C26-(1,3-dioxolanyl)-12,13-desoxyepothilone B

Mark D. Chappell, Christina R. Harris, Scott D. Kuduk, Aaron Balog, Zhicai Wu, Fei Zhang, Chul Bom Lee, Shawn J. Stachel, Samuel J. Danishefsky, Ting-Chao Chou, Yongbiao Guan

J. Org. Chem., 67, 7730-7736 (2002). DOI

The synthesis, discovery, and development of a highly promising class of microtubule stabilization agents:
Curative effects of desoxyepothilones B and F against human tumor xenografts in nude mice

Ting-Chao Chou, Owen A. O’Connor, William P. Tong, Yongbiao Guan, Zui-Guo Zhang, Shawn J. Stachel, Chulbom Lee, Samuel J. Danishefsky

Proc. Natl. Acad. Sci. U.S.A. 98, 8113-8118 (2001). DOI

A New Class of Microtubule Stabilization Agents: Curative Effect of Desoxyepothilone B and F
against Human Tumor Xenografts in Nude Mice

T.-C. Chou, Y. Guan, X.-G. Zhang, C. Lee, S. J. Stachel, J. R. Bertino, and S. J. Danishefsky

Proc. Am. Assoc. Cancer Res. 42, 371 (2001).

On the Interactivity of Complex Synthesis and Tumor Pharmacology in the Drug Discovery Process:
The Total Synthesis and Comparative in vivo Evaluations of the 15-Aza Epothilones

Shawn J. Stachel, Chul Bom Lee, Maria Spassova, Mark D. Chappell, William G. Bornmann, Samuel J. Danishefsky, Ting-Chao Chou, Yongbiao Guan

J. Org. Chem. 66, 4369-4378 (2001). DOI

Insights into Long-Range Structural Effects on the Stereochemistry of Aldol Condensations:
A Practical Total Synthesis of Desoxyepothilone F

Chul Bom Lee, Zhicai Wu, Fei Zhang, Mark D. Chappell, Shawn J. Stachel, Ting-Chao Chou, Yongbiao Guan, Samuel J. Danishefsky

J. Am. Chem. Soc. 123, 5249-5259 (2001). DOI

Total Synthesis and Antitumor Activity of 12,13-Desoxyepothilone F: An Unexpected Solvolysis Problem at C15,
Mediated by Remote Substitution at C21

Chul Bom Lee, Ting-Chao Chou, Xiu-Guo Zhang, Zhi-Guang Wang, Scott D. Kuduk, Mark D. Chappell, Shawn J. Stachel, Samuel J. Danishefsky

J. Org. Chem. 65, 6525-6533 (2000). DOI

On the Total Synthesis and Preliminary Biological Evaluations of 15(R) and 15(S) Aza-dEpoB:
A Mitsunobu Inversion at C15 in Pre-Epothilone Fragments

Shawn J. Stachel, Mark D. Chappell, Chul Bom Lee, Samuel J. Danishefsky, Ting-Chao Chou, Lifeng He, Susan B. Horwitz

Org. Lett. 2, 1637-1639 (2000). DOI

En Route to a Plant Scale Synthesis of the Promising Antitumor Agent 12,13-Desoxyepothilone B

Mark D. Chappell, Shawn J. Stachel, Chul Bom Lee, and Samuel J. Danishefsky

Org. Lett. 2, 1633-1636 (2000). DOI

gem-Diacetates as Carbonyl Surrogates for Asymmetric Synthesis. Total Syntheses of Sphingofungins E and F

Barry M. Trost, Chulbom Lee

J. Am. Chem. Soc. 123, 12191-12201 (2001). DOI

Geminal-Dicarboxylates as Carbonyl Surrogates for Asymmetric Synthesis. Part II. Scope and Applications

Barry M. Trost, Chul Bom Lee

J. Am. Chem. Soc. 123, 3687-3696 (2001). DOI

Geminal-Dicarboxylates as Carbonyl Surrogates for Asymmetric Synthesis.
Part I. Asymmetric Addition of Malonate Nucleophiles

Barry M. Trost, Chul Bom Lee

J. Am. Chem. Soc. 123, 3671-3686 (2001). DOI

Transition Metal-Catalyzed Asymmetric Allylic Alkylation (AAA) Reactions

Barry M. Trost and Chul Bom Lee

"Catalytic Asymmetric Synthesis (2nd Ed.)," I. Ojima Ed.; Wiley-VCH, New York, NY, 2000, Chapter 8E, pp 593-649.

α-Acetoxysulfones as “Chiral Aldehyde” Equivalents

Barry M. Trost , Matthew L. Crawley , and Chul Bom Lee

J. Am. Chem. Soc. 122, 6120-6121 (2000). DOI

A New Strategy for Synthesis of Sphingosine Analogues. Sphingofungin F

Barry M. Trost and Chul Bom Lee

J. Am. Chem. Soc. 120, 6818-6819 (1998). DOI

Asymmetric Alkylation of Allylic gem-Dicarboxylates

Barry M. Trost, Chul Bom Lee, Jochen M. Weiss

J. Am. Chem. Soc. 117, 7247-7248 (1995). DOI

β-Alkoxyacrylates in radical cyclizations: Remarkably efficient oxacyle synthesis

Eun Lee, Jin Sung Tae, Chulbom Lee, Cheol Min Park

Tetrahedron Lett. 34, 4831-4834 (1993). DOI

Radical isomerization via intramolecular ipso substitution of aryl ethers: Aryl translocation from oxygen to carbon

Eun Lee, Chulbom Lee, Jin Sung Tae, Ho Sung Whang, and Kap Sok Li

Tetrahedron Lett. 34, 2343-2346 (1993). DOI